Ractopamine

• Description:

  Ractopamine (LY031537 free base) is a potent β-adrenergic receptor (βAR) agonist with Kd value of ~25 nM for pig β1AR and β2AR. Ractopamine is linked to protein metabolism. Ractopamine is structurally similar to the natural catecholamines epinephrine and norepinephrine, and binds with high affinity to βAR in pig adipose and muscle tissue. Ractopamine can be used for researching to increase lean tissue growth and improve production efficiency in pigs[1][2][3].

• Product Name Alternative:

  LY031537 (free base)

• UNSPSC:

  12352005

• Target:

  Adrenergic Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein; Neuronal Signaling

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/ractopamine.html

• Solubility:

  10 mM in DMSO

• Smiles:

  OC(CNC(C)CCC1=CC=C(O)C=C1)C2=CC=C(O)C=C2

• Molecular Formula:

  C18H23NO3

• Molecular Weight:

  301.38

• References & Citations:

  [1]Athayde NB, et al. Stress susceptibility in pigs supplemented with ractopamine. J Anim Sci. 2013;91 (9) :4180-4187. |[2]Anderson PT, et al. Ractopamine increases total and myofibrillar protein synthesis in cultured rat myotubes. J Nutr. 1990;120 (12) :1677-1683.|[3]S. E. Mills, Biological basis of the ractopamine response, Journal of Animal Science, Volume 80, Issue E-suppl_2, 2002, Pages E28–E32

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  β adrenergic receptor

• CAS Number:

  [97825-25-7]