GCPII-IN-1 (TFA)

GCPII-IN-1 (TFA)

• CAS Number: 1269794-89-9
• UNSPSC Description: GCPII-IN-1 TFA is a glutamate carboxypeptidase II (GCPII, or PSMA) inhibitor scaffold with a Ki of 44.3 nM[1].
• Target Antigen: Carboxypeptidase
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/gcpii-in-1-tfa.html
• Solubility: H2O : 160 mg/mL (ultrasonic)
• Smiles: OC(C(F)(F)F)=O.NCCCC[C@@H](C(O)=O)NC(N[C@H](C(O)=O)CCC(O)=O)=O
• Molecular Weight: 433.33
• References & Citations: [1]Jan Tykvart, et al. Rational design of urea-based glutamate carboxypeptidase II (GCPII) inhibitors as versatile tools for specific drug targeting and delivery. Bioorg Med Chem. 2014 Aug 1;22(15):4099-108.
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported