Products for Research Use Only
RegisterLogin

Anti-Botch Antibody

CAT: 1303-75-181Size: 100 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:1303-75-181Size:100 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Cation transport regulator-like protein 1, Glutathione-Specific Gamma-Glutamylcyclotransferase 1 or Botch1 is encoded by the gene CHAC1. Chac1 is a member of the gamma-glutamylcyclotransferase family. It is an enzyme that acts to catalyze the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Chac1 is involved in neuronal differentiation by deglycination of the Notch receptor, which prevents receptor maturation and inhibits Notch signaling. CHAC1 is expressed in tissues including brain (forebrain and anterior spinal cord), and heart. Diseases associated with CHAC1 include Ovarian Embryonal Carcinoma and Ovarian Cancer.
Description
Our Anti-Botch mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N116/14. It detects human, mouse, and rat Botch, and is purified by Protein A chromatography. It is great for use in ICC, WB.
Short Description
Our Anti-Botch mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N116/14. It detects human, mouse, and rat Botch, and is purified by protein a chromatography. It is great for use in WB, IHC, ICC, ELISA.
Synonyms
Glutathione-specific gamma-glutamylcyclotransferase 1 (Gamma-GCG 1) (EC 4.3.2.7) (Blocks Notch protein) (Botch) (Cation transport regulator-like protein 1) (Neuroprotective protein 7)
Gene Name
Chac1 Botch Npg7
UniProt
B3STU3
Host
Mouse
Reactivity
Human, Mouse, and Rat
Immunogen
Fusion protein amino acids 1-222 (full-length) of rat Botch1 (accession number B3STU3.1) produced recombinantly in E. Coli
Target
Botch
Clonality
Monoclonal
Isotype
IgG1
Clone
N116/14
Type
Primary Antibody
Applications
WB, IHC, ICC, ELISA
Field of Research
Neurogenesis and Development
Concentration
1 mg/mL
Format
Purified by Protein A chromatography
Buffer
10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.109
Molecular Weight
25 kDa
Shipping Conditions
Shipped on ice packs
Storage Conditions
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Notes
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
WB Dilution
1:2000
Specificity
No cross-reactivity against Botch2/Chac2
Quality Control
Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.
Recommended Usage
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
Physical Properties
Liquid
Immunogen Species
Rat
ICC Quality Control
1
Conjugate
Unconjugated
RRID
AB_2079324

Related Products

CatalogName
75-364Anti-LRRTM2 Antibody
75-426-020Anti-ATAT1 Antibody
RP-4003-020Anti-Fibronectin Antibody
77-522Anti-SARM1 Antibody
75-512Anti-TMEM119 Antibody
75-498Anti-VAPA Antibody
75-487Anti-ZIP3 Antibody
75-423Anti-WRN Antibody
73-478Anti-VGAT Antibody
75-474Anti-Proser1 Antibody

Alternative Products

CatalogName
E55A15142Botch Antibody
HP690013-01Anti-Botch Antibody (N116/10)
HP690023-01Anti-Botch Antibody (N116/14)
GTR18686539-01Botch Mouse Monoclonal Antibody
STJ118549Anti-Anti-MARCH6 Antibody antibody
STJ114819Anti-Anti-SEPT5 Antibody antibody
STJ117759Anti-Anti-SEPT12 Antibody antibody
STJ114828Anti-Anti-MARCH8 Antibody antibody
STJ118990Anti-Anti-SEPT3 Antibody antibody
STJ111369Anti-Anti-SEPT9 Antibody antibody

Popular Products