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Anti-Complement Factor H (beta-1H-Globulin) Antibody

CAT: 1303-GAU 020-03-04Size: 400 uLDry Ice: NoHazardous: No
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CAT#:1303-GAU 020-03-04Size:400 uL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Factor H is a regulatory factor of the alternative pathway of complement activation. Factor H is a glycoprotein consisting of a single polypeptide chain with a molecular mass of 150 kDa.
Description
Our mouse Complement Factor H (beta-1H-globulin) monoclonal antibody from Antibodies Incorporated is produced in-house from clone L20/3. It detects human Complement Factor H (beta-1H-globulin) and is Protein A or Protein G purified. Works in ELISA, WB.
Synonyms
CFH, AHUS1, AMBP1, ARMD4, ARMS1, CFHL3, FH, FHL1, HF, HF1, HF2, HUS, complement factor H, H factor 1 (complement), H factor 2 (complement), adrenomedullin binding protein, age-related maculopathy susceptibility 1, beta-1-H-globulin, beta-1H, factor H, factor H-like 1
Gene Name
CFH
NCBI Gene ID
3075
UniProt
P08603
Host
Mouse
Reactivity
Human
Immunogen
Human Factor H
Target
Complement Factor H (beta-1H-globulin)
Clonality
Monoclonal
Isotype
IgG2a κ
Clone
L20/3
Type
Primary Antibodies
Applications
ELISA, WB
Concentration
1 mg/mL ±15%
Format
Protein A or Protein G purified
Buffer
0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide
Molecular Weight
150 kDa
Shipping Conditions
Shipped on ice packs
Storage Conditions
2-8°C without exposure to light
Notes
BSA free
Specificity
GAU 020-03 is specific for complement factor H in human serum and plasma. Epitope specificity differs from that of GAU 018-03.
Brand
Antibodies Inc (via BioPorto acquisition)
Recommended Usage
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
Physical Properties
Liquid
Immunogen Species
Human

UniProtKB · P08603

Complement factor H

CFAH_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P08603
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CFH
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
A5PL14, P78435, Q14570, Q2TAZ5, Q38G77, Q5TFM3, Q8N708, Q9NU86
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Disease

Age-related macular degenerationDisease variantHemolytic uremic syndrome

Coding sequence diversity

Alternative splicing

Biological process

Complement alternate pathwayHost-virus interactionImmunityInnate immunity

PTM

Disulfide bondGlycoproteinSulfation

Domain

RepeatSignalSushi

Cellular component

Secreted

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