Recombinant Mouse Adenosine deaminase (Ada)

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CAT:

399-CSB-EP001268MO-02

Size:

100 µg

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Recombinant Mouse Adenosine deaminase (Ada)

Gene Name: Ada
UniProt: P03958
Expression Region: 2-352aa
Organism: Mus musculus
Target Sequence: AQTPAFNKPKVELHVHLDGAIKPETILYFGKKRGIALPADTVEELRNIIGMDKPLSLPGFLAKFDYYMPVIAGCREAIKRIAYEFVEMKAKEGVVYVEVRYSPHLLANSKVDPMPWNQTEGDVTPDDVVDLVNQGLQEGEQAFGIKVRSILCCMRHQPSWSLEVLELCKKYNQKTVVAMDLAGDETIEGSSLFPGHVEAYEGAVKNGIHRTVHAGEVGSPEVVREAVDILKTERVGHGYHTIEDEALYNRLLKENMHFEVCPWSSYLTGAWDPKTTHAVVRFKNDKANYSLNTDDPLIFKSTLDTDYQMTKKDMGFTEEEFKRLNINAAKSSFLPEEEKKELLERLYREYQ
Tag: C-terminal 6xHis-tagged
Source: E.coli
Field of Research: Signal Transduction
Assay Type: Developed Protein
Relevance: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. Acts as a positive regulator of T-cell coactivation, by binding DPP4. Its interaction with DPP4 regulates lymphocyte-epithelial cell adhesion. Enhances dendritic cell immunogenicity by affecting dendritic cell costimulatory molecule expression and cytokines and chemokines secretion. Enhances CD4+ T-cell differentiation and proliferation. Acts as a positive modulator of adenosine receptors ADORA1 and ADORA2A, by enhancing their ligand affinity via conformational change. Stimulates plasminogen activation. Plays a role in male fertility. Plays a protective role in early postimplantation embryonic development.
Purity: Greater than 95% as determined by SDS-PAGE.
Activity: Not Test
Length: Full Length of Mature Protein
Form: Liquid or Lyophilized powder
Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Molecular Weight: 46.8 kDa
Storage Conditions: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.

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Cat	Name
CSB-EP001268MO-02	Recombinant Mouse Adenosine deaminase (Ada)
CSB-EP001268MO-03	Recombinant Mouse Adenosine deaminase (Ada)
CSB-EP001268MO-01	Recombinant Mouse Adenosine deaminase (Ada)
CSB-EL001375MO-02	Mouse Adenosine receptor A1(ADORA1) ELISA kit
CSB-EL001375MO-01	Mouse Adenosine receptor A1(ADORA1) ELISA kit
CSB-EL001377MO-01	Mouse Adenosine receptor A2b(ADORA2B) ELISA kit
CSB-EP859990MO-01	Recombinant Mouse Double-stranded RNA-specific adenosine deaminase (Adar), partial
CSB-EP859990MO-03	Recombinant Mouse Double-stranded RNA-specific adenosine deaminase (Adar), partial
CSB-EL001375MO-03	Mouse Adenosine receptor A1(ADORA1) ELISA kit
CSB-EL001376MO-04	Mouse Adenosine receptor A2a(ADORA2A) ELISA kit