2-Deoxy-2-fluoro-L-fucose
CAT:
804-HY-116705-06
Size:
100 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
2-Deoxy-2-fluoro-L-fucose
- Product Name Alternative: Adonitol-3-13C; Adonite-3-13C
- CAS Number: 70763-62-1
- UNSPSC Description: 2-Deoxy-2-fluoro-L-fucose, an L-fucose analog, is a fucosylation inhibitor. 2-Deoxy-2-fluoro-L-fucose inhibits de novo synthesis of GDP-fucose in mammalian cells. Fucosylation is a relatively well-defined biomarker for progression in many human cancers; for example, pancreatic and hepatocellular carcinoma[1].
- Target Antigen: Others
- Type: Reference compound
- Related Pathways: Others
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/2-deoxy-2-fluoro-l-fucose.html
- Purity: 99.99
- Solubility: DMSO : 100 mg/mL (ultrasonic)
- Smiles: O=C[C@@H](F)[C@@H]([C@@H]([C@H](C)O)O)O
- Molecular Weight: 166.15
- References & Citations: [1]Herrera H, et al. Core-Fucosylated Tetra-Antennary N-Glycan Containing A Single N-Acetyllactosamine Branch Is Associated with Poor Survival Outcome in Breast Cancer. Int J Mol Sci. 2019;20(10):2528. Published 2019 May 23.
- Shipping Conditions: Blue Ice
- Storage Conditions: -20°C (Powder, protect from light, stored under nitrogen)
- Clinical Information: No Development Reported