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XQ2B

CAT: 0804-HY-P5997-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-P5997-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
XQ2B is a specific cGAS inhibitor targeting protein-DNA interaction and phase separation. XQ2B markedly reduces ISD-induced Autophagy. XQ2B inhibits herpes simplex virus 1 (HSV-1) -induced antiviral immune responses and enhances HSV-1 infection[1].
CAS Number
2104728-28-9
UNSPSC
12352209
Target
Autophagy; Cyclic GMP-AMP Synthase
Type
Peptides
Related Pathways
Autophagy; Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/xq2b.html
Purity
99.45
Solubility
H2O : 100 mg/mL (ultrasonic)
Smiles
O=C([C@H](CC(C)C)NC([C@H](CCCNC(N)=N)NC([C@H](C(C)C)NC([C@H]1N(C([C@@H](CC2=CC=CC=C2)NC([C@H](CC(C)C)NC([C@@H](N3)CCCNC(N)=N)=O)=O)=O)CCC1)=O)=O)=O)N[C@@H](C(N[C@@H](C)C(N[C@]([C@H](O)C)([H])C3=O)=O)=O)CC4=CC=CC=C4
Molecular Formula
C59H92N16O11
Molecular Weight
1201.46
References & Citations
[1]Wang X, et al. Development of cyclopeptide inhibitors of cGAS targeting protein-DNA interaction and phase separation. Nat Commun. 2023 Oct 2;14 (1) :6132.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported

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CatalogName
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