Products for Research Use Only

DOTA-XYIMSR-01

CAT: 0013-GTR19338543-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19338543-01Size:50 mg
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Description
DOTA-XYIMSR-01 is a molecular probe targeting CAIX, capable of being labeled with 177Lu for the treatment and localization of malignant gliomas. The uptake of [177Lu]Lu-XYIMSR-01 in U87MG tumors is 6.19% injected dose per gram (% ID/g), with a tumor-to-muscle uptake ratio of 20.14. In an orthotopic glioma model, co-administration with temozolomide significantly enhances survival rates and inhibits tumor growth in mice. DOTA-XYIMSR-01 shows potential for research in the field of cancer treatment.
CAS Number
2051527-54-7
Field of Research
Metabolism Research
Molecular Weight
1461.57
Storage Conditions
-20°C
Notes
For research use only.