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EN219-alkyne

CAT: 0013-GTR19337419-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19337419-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
EN219-alkyne is an alkyne-functionalized EN219 probe. EN219 is a synthetic covalent ligand with moderate specificity for the N-terminal cysteine (C8) of RNF114, exhibiting an IC50 of 470 nM. It inhibits RNF114-mediated autoubiquitination and p21 ubiquitination. EN219-alkyne acts as a click chemistry reagent, containing an alkyne group that can undergo a copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing azide groups.
Storage Conditions
-20°C
Notes
For research use only.

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