Lombazole

CAT: 0804-HY-118843Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-118843Size:1 Each
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Description
Lombazole is an antimicrobial compound with activity that inhibits cell membrane synthesis. Lombazole had little effect on K+ permeability in S. aureus. Lombazole inhibited only de novo synthesis of cell enclosure in S. aureus, and this effect occurred before growth was affected. The main effect of lombazole was through inhibition of lipid synthesis. Lombazole may have an effect on key steps in lipid biosynthesis, as inferred from the lack of changes in lipid patterns after treatment. Lombazole also inhibited the sterol C-14 demethylation step in Candida albicans[1].
CAS Number
[60628-98-0]
UNSPSC
12352005
Target
Potassium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/lombazole.html
Smiles
ClC1=C(C(N2C=NC=C2)C3=CC=C(C4=CC=CC=C4)C=C3)C=CC=C1
Molecular Formula
C22H17ClN2
Molecular Weight
344.84
References & Citations
[1]Action of lombazole, and inhibitor of fungal ergosterol biosynthesis, on Staphylococcus epidermidis
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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