Talc

• Description:

  Talc, a naturally occurring mineral composed primarily of magnesium, silicon and oxygen, is used in many cosmetics, from baby powder to blush[1][2].

• UNSPSC:

  12352300

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  Biochemical Assay Reagents; Reactive Oxygen Species (ROS)

• Type:

  Reference compound

• Related Pathways:

  Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/talc.html

• Purity:

  97.0

• Solubility:

  DMSO : < 1 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : < 0.1 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles:

  O[Si] (O) =O.[0.75 Mg]

• Molecular Formula:

  H2O3Si

• Molecular Weight:

  78.10

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Talc.|[2]Radić I, et al., Immunosuppression induced by talc granulomatosis in the rat. Clin Exp Immunol. 1988 Aug;73 (2) :316-21.|[3]Mandarino A, et al., The effect of talc particles on phagocytes in co-culture with ovarian cancer cells. Environ Res. 2020 Jan;180:108676.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  Launched

• CAS Number:

  14807-96-6