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Rivaroxaban-d4

CAT: 0804-HY-50903SSize: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-50903SSize:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Rivaroxaban-d4 (BAY 59-7939-d4) is a deuterium labeled Rivaroxaban. Rivaroxaban is a highly potent, selective and direct Factor Xa (FXa) inhibitor, achieving a strong gain in anti-FXa potency (IC50 0.7 nM; Ki 0.4 nM) [1][2].
CAS Number
1132681-38-9
Product Name Alternative
BAY 59-7939-d4
UNSPSC
12352005
Hazard Statement
H302
Target
Factor Xa
Type
Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Purity
98.73
Solubility
10 mM in DMSO|DMSO : 50mg/mL (ultrasonic)
Smiles
O=C(C1=CC=C(Cl)S1)NC[C@H]2CN(C3=C([2H])C([2H])=C(N4C(COCC4)=O)C([2H])=C3[2H])C(O2)=O
Molecular Formula
C19H14D4ClN3O5S
Molecular Weight
439.91
Precautions
H302
References & Citations
[1]Roehrig S, et al. Discovery of the novel antithrombotic agent 5-chloro-N- ({ (5S) -2-oxo-3- [4- (3-oxomorpholin-4-yl) phenyl]-1,3-oxazolidin-5-yl}methyl) thiophene- 2-carboxamide (BAY 59-7939) : an oral, direct factor Xa inhibitor. J Med Chem. 2005 Sep 22;48 (19) |[2]Perzborn E, et al. In vitro and in vivo studies of the novel antithrombotic agent BAY 59-7939--an oral, direct Factor Xa inhibitor. J Thromb Haemost. 2005 Mar;3 (3) :514-21.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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