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Protirelin

CAT: 0804-HY-P0002-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-P0002-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Protirelin is a highly conserved neuropeptide that exerts the hormonal control of thyroid-stimulating hormone (TSH) levels as well as neuromodulatory functions.
CAS Number
24305-27-9
Product Name Alternative
Thyrotropin-releasing-hormone; TRH
UNSPSC
12352209
Hazard Statement
H302, H315, H319, H335
Target
Endogenous Metabolite; Thyroid Hormone Receptor
Type
Peptides
Related Pathways
Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/Protirelin.html
Purity
99.98
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
O=C(N)[C@H]1N(C([C@H](CC2=CNC=N2)NC([C@H](CC3)NC3=O)=O)=O)CCC1
Molecular Formula
C16H22N6O4
Molecular Weight
362.38
Precautions
H302, H315, H319, H335
References & Citations
[1]Van Sinay E, et al. Evolutionarily conserved TRH neuropeptide pathway regulates growth in Caenorhabditis elegans. Proc Natl Acad Sci U S A. 2017 May 16;114 (20) :E4065-E4074.|[2]Noda Y, et al. Hyperthermia induced by thyrotropin-releasing hormone (TRH, Protirelin) in the rat. Kurume Med J. 1979;26 (2) :107-12.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)
Scientific Category
Peptides
Clinical Information
Launched
Citation 01
Cell Rep. 2024 Nov 9;43 (11) :114962.|Nat Immunol. 2024 Apr;25 (4) :659-670.|Obesity. 2024 Aug;32 (8) :1483-1493.

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