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JC-1

CAT: 0013-GTR19318809-02Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19318809-02Size:5 mg
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Description
JC-1 is a lipophilic fluorescent dye widely used to assess mitochondrial membrane potential in both in vitro and in vivo studies. It exhibits a potential-dependent shift from green monomer fluorescence to red J-aggregate emission, making it a key tool in apoptosis, neurobiology, and toxicology research.
CAS Number
3520-43-2
Product Name Alternative
Inhibit, JC 1, JC1, JC-1, Inhibitor, CBIC 2, CBIC2, CBIC-2
Purity
>98%
Bioactivity
Mitochondrial membrane potential probe
Form
Powder
Solubility
DMSO (up to 20 mg/ml)
Molecular Weight
652.23
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

5,5',6,6'-Tetrachloro-1,1',3,3'-tetraethylbenzimidazolocarbocyanine iodide

1,1',3,3'-tetraethyl-5,5',6,6'-tetrachloroimidacarbocyanine iodide is a cyanine dye and an organic iodide salt. It has a role as a fluorochrome. It contains a 1,1',3,3'-tetraethyl-5,5',6,6'-tetrachloroimidacarbocyanine.

CAS Number3520-43-2
PubChem CID5492929
IUPAC Name5,6-dichloro-2-[(E)-3-(5,6-dichloro-1,3-diethylbenzimidazol-3-ium-2-yl)prop-2-enylidene]-1,3-diethylbenzimidazole iodide
Molecular FormulaC25H27Cl4IN4
Molecular Weight652.2
Topological Polar Surface Area15.3
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count3
Rotatable Bond Count6
Heavy Atom Count34
Formal Charge0
Complexity625
SMILES
CCN1C2=CC(=C(C=C2[N+](=C1/C=C/C=C3N(C4=CC(=C(C=C4N3CC)Cl)Cl)CC)CC)Cl)Cl.[I-]
InChI
InChI=1S/C25H27Cl4N4.HI/c1-5-30-20-12-16(26)17(27)13-21(20)31(6-2)24(30)10-9-11-25-32(7-3)22-14-18(28)19(29)15-23(22)33(25)8-4;/h9-15H,5-8H2,1-4H3;1H/q+1;/p-1
InChIKey
FYNNIUVBDKICAX-UHFFFAOYSA-M
Chemical Structure
2D Structure
2D structure of 5,5',6,6'-Tetrachloro-1,1',3,3'-tetraethylbenzimidazolocarbocyanine iodide
CAS: 3520-43-2
CID: 5492929
Formula: C25H27Cl4IN4
MW: 652.2
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight652.2
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count3
Rotatable Bond Count6
Exact Mass652.00051
Monoisotopic Mass650.00346
Topological Polar Surface Area15.3 Ų
Heavy Atom Count34
Formal Charge0
Complexity625
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count2
Compound Is CanonicalizedYes

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