(-) -Cedrene

• Description :

  (-) -Cedrene (α-cedrene) is a major constituent that can be found in essential oils. (-) -Cedrene (α-cedrene) is a natural, orally active ligand of mouse olfactory receptor 23, which induces skeletal muscle hypertrophy in mice. (-) -Cedrene exhibits trypanocidal (Trypanosoma b. brucei) (IC50 = 4.07 μg/mL) . (-) -Cedrene is antileukemic in vitro (IC50 = 22.2 μg/mL) . (-) -Cedrene has antimicrobial activity against anaerobic bacteria and yeast. (-) -Cedrene exhibits anti-obesity activity[1][2].

• CAS Number :

  [469-61-4]

• Product Name Alternative :

  α-cedrene

• UNSPSC :

  12352211

• Hazard Statement :

  H315, H319, H400

• Target :

  Bacterial

• Type :

  Natural Products

• Related Pathways :

  Anti-infection

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Cancer; Infection; Metabolic Disease

• Assay Protocol :

  https://www.medchemexpress.com/minus-cedrene.html

• Concentration :

  10mM

• Purity :

  98.0

• Solubility :

  DMSO : 12.5 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles :

  C[C@H]1[C@]2(C[C@H]3C(C)=CC2)[C@](CC1)([H])C3(C)C

• Molecular Formula :

  C15H24

• Molecular Weight :

  204.35

• Precautions :

  H315, H319, H400

• References & Citations :

  [1]Tae Hwan Kim, et al. In Vivo Absorption and Disposition of α-Cedrene, a Sesquiterpene Constituent of Cedarwood Oil, in Female and Male Rats. Drug Metab Pharmacokinet. 2015 Apr;30 (2) :168-73.|[2]Tong, T., et al., (2018) . α-Cedrene, a Newly Identified Ligand of MOR23, Increases Skeletal Muscle Mass and Strength. Molecular nutrition & food research, 62 (15), e1800173.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported