(-) -Cedrene

CAT: 0804-HY-135190-01Size: 1 mLDry Ice: NoHazardous: No
CAT#:0804-HY-135190-01Size:1 mL
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Description
(-) -Cedrene (α-cedrene) is a major constituent that can be found in essential oils. (-) -Cedrene (α-cedrene) is a natural, orally active ligand of mouse olfactory receptor 23, which induces skeletal muscle hypertrophy in mice. (-) -Cedrene exhibits trypanocidal (Trypanosoma b. brucei) (IC50 = 4.07 μg/mL) . (-) -Cedrene is antileukemic in vitro (IC50 = 22.2 μg/mL) . (-) -Cedrene has antimicrobial activity against anaerobic bacteria and yeast. (-) -Cedrene exhibits anti-obesity activity[1][2].
CAS Number
[469-61-4]
Product Name Alternative
α-cedrene
UNSPSC
12352211
Hazard Statement
H315, H319, H400
Target
Bacterial
Type
Natural Products
Related Pathways
Anti-infection
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cancer; Infection; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/minus-cedrene.html
Concentration
10mM
Purity
98.0
Solubility
DMSO : 12.5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
C[C@H]1[C@]2(C[C@H]3C(C)=CC2)[C@](CC1)([H])C3(C)C
Molecular Formula
C15H24
Molecular Weight
204.35
Precautions
H315, H319, H400
References & Citations
[1]Tae Hwan Kim, et al. In Vivo Absorption and Disposition of α-Cedrene, a Sesquiterpene Constituent of Cedarwood Oil, in Female and Male Rats. Drug Metab Pharmacokinet. 2015 Apr;30 (2) :168-73.|[2]Tong, T., et al., (2018) . α-Cedrene, a Newly Identified Ligand of MOR23, Increases Skeletal Muscle Mass and Strength. Molecular nutrition & food research, 62 (15), e1800173.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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