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1-Hydroxy-2-naphthoic acid

CAT: 0804-HY-W016103-01Size: 25 gDry Ice: NoHazardous: No
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CAT#:0804-HY-W016103-01Size:25 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
1-Hydroxy-2-naphthoic acid is a polycyclic aromatic hydrocarbon (PAHs) degradation intermediate, mainly formed during the microbial degradation of aromatic hydrocarbons such as phenanthrene and naphthalene. 1-Hydroxy-2-naphthoic acid can undergo further hydroxylation, resulting in the naphthalene degradation pathway, or direct ring opening, leading to the phthalic acid pathway. 1-Hydroxy-2-naphthoic acid can be eliminated by introducing a heterologous salicylate hydroxylase gene (nahG) into the degrading bacterium[1][2].
CAS Number
86-48-6
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Bacterial
Type
Natural Products
Related Pathways
Anti-infection
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/1-hydroxy-2-naphthoic-acid.html
Purity
99.83
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(O)C1=CC=C2C=CC=CC2=C1O
Molecular Formula
C11H8O3
Molecular Weight
188.18
Precautions
H315, H319, H335
References & Citations
[1]Karale MA, et al. A Plasmid Induces Biodegradation of Pyrene by Bacillus cereus C7 and Identification of Its Degradation Metabolites. Indian J Microbiol. 2025 Jun;65 (2) :1047-1057.|[2]Ma J, et al. Study and Modification of the Polycyclic Aromatic Hydrocarbon Degradation Gene Cluster in Burkholderia sp. FM-2. Microorganisms. 2025 Sep 6;13 (9) :2079. PMID: 41011412; PMCID: PMC12472010.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported