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VPC-70063

CAT: 0804-HY-147291-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-147291-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
VPC-70063 is a potent Myc-Max inhibitor with an IC50 value of 8.9 μM for Myc-Max transcriptional activity inhibition. VPC-70063 reduces UBE2C promotor activity and AR-V7 levels, and induces PARP cleavage. VPC-70063 induces apoptosis and blocks Myc-Max interactions with DNA. VPC-70063 can be used for researching anticancer[1].
CAS Number
13571-44-3
UNSPSC
12352005
Target
Apoptosis; c-Myc; PARP
Type
Reference compound
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/vpc-70063.html
Purity
99.92
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
FC(F)(C1=CC(NC(NCC2=CC=CC=C2)=S)=CC(C(F)(F)F)=C1)F
Molecular Formula
C16H12F6N2S
Molecular Weight
378.34
References & Citations
[1]Carabet LA, et al. Computer-aided drug discovery of Myc-Max inhibitors as potential therapeutics for prostate cancer. Eur J Med Chem. 2018 Dec 5;160:108-119.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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