Aspartame-d3

Aspartame-d3

• CAS Number: 1356841-28-5
• UNSPSC Description: Aspartame-d3 is the deuterium labeled Aspartame. Aspartame (SC-18862) is a methyl ester of a dipeptide. Aspartame can be used as a synthetic nonnutritive sweetener. Aspartame is composed of phenylalanine (50%), aspartic acid (40%) and methanol (10%)[1][2].
• Target Antigen: Isotope-Labeled Compounds
• Type: Isotope-Labeled Compounds
• Related Pathways: Others
• Field of Research: Neurological Disease
• Solubility: 10 mM in DMSO
• Smiles: OC(C[C@H](N)C(N[C@H](C(OC([2H])([2H])[2H])=O)CC1=CC=CC=C1)=O)=O
• Molecular Weight: 297.32
• References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Magnuson, B.A., et al., Aspartame: a safety evaluation based on current use levels, regulations, and toxicological and epidemiological studies. Crit Rev Toxicol, 2007. 37(8): p. 629-727.|[3]Humphries, P., E. Pretorius, and H. Naude, Direct and indirect cellular effects of aspartame on the brain. Eur J Clin Nutr, 2008. 62(4): p. 451-62.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported