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SERTlight

CAT: 0804-HY-D2335-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-D2335-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SERTlight is a fluorescent agent that can specifically label serotonergic neuronal cell bodies, dendrites, and axonal projections as fluorescent substrates of the serotonin transporter (SERT) . SERTlight is orthogonal to various genetically encoded sensors in terms of optics, pharmacology, and operation, enabling multiple imaging. SERTlight allows the use of GRAB5HT sensors to label distal 5HT axonal projections and simultaneously image the release of endogenous 5HT, providing a new multifunctional molecular tool for studying serotonergic systems[1].
UNSPSC
12171500
Target
Fluorescent Dye
Type
Dye Reagents
Related Pathways
Others
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/sertlight.html
Solubility
10 mM in DMSO
Smiles
OC1=CC(N2)=C(C=C(C2=O)CCN)C=C1F.FC(F)(C(O)=O)F
Molecular Formula
C13H12F4N2O4
Molecular Weight
336.24
References & Citations
[1]Lee WL, et al. Molecular Design of SERTlight: A Fluorescent Serotonin Probe for Neuronal Labeling in the Brain. J Am Chem Soc. 2024;146 (14) :9564-9574.
Shipping Conditions
Room temperature
Scientific Category
Dye Reagents
Clinical Information
No Development Reported

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CatalogName
T209835-01SERTlight

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