Phenylpyropene A

• UNSPSC Description:

  Phenylpyropene A, a fungal metabolite, is a potent acyl-CoA: cholesterol acyltransferase (ACAT) inhibitor with an IC50 of 0.8 μM[1].

• Target Antigen:

  Acyltransferase

• Type:

  Natural Products

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/phenylpyropene-a.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1OC(C2=CC=CC=C2)=CC3=C1[C@H](O)[C@@]4([H])[C@]([C@@H](OC(C)=O)C[C@@]5([H])[C@](C)(COC(C)=O)[C@@H](OC(C)=O)CC[C@@]54C)(C)O3

• Molecular Weight:

  582.64

• References & Citations:

  [1]R Obata, et al. Chemical modification and structure-activity relationships of pyripyropenes. 3. Synthetic conversion of pyridine-pyrone moiety. J Antibiot (Tokyo). 1997 Mar;50(3):229-36.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  189564-20-3