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Pinosylvin

CAT: 0804-HY-N2387-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N2387-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Pinosylvin is a pre-infectious stilbenoid toxin isolated from the heartwood of Pinus species, has anti-bacterial activities[1]. Pinosylvin is a resveratrol analogue, can induce cell apoptosis and autophapy in leukemia cells[2].
CAS Number
22139-77-1
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; Autophagy; Bacterial
Type
Natural Products
Related Pathways
Anti-infection; Apoptosis; Autophagy
Applications
Cancer-programmed cell death
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/pinosylvin.html
Purity
99.94
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC1=CC(/C=C/C2=CC=CC=C2)=CC(O)=C1
Molecular Formula
C14H12O2
Molecular Weight
212.24
Precautions
H302, H315, H319, H335
References & Citations
[1]Lee SK, et al. Antibacterial and antifungal activity of pinosylvin, a constituent of pine.Fitoterapia. 2005 Mar;76 (2) :258-60.|[2]Roupe KA, et al. Pharmacokinetics of selected stilbenes: rhapontigenin, piceatannol and pinosylvin in rats.J Pharm Pharmacol. 2006 Nov;58 (11) :1443-50.|[3]Song J, et al. Pinosylvin enhances leukemia cell death via down-regulation of AMPKα expression. Phytother Res. 2018 Oct;32 (10) :2097-2104.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported