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HN37

CAT: 0804-HY-145016-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-145016-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
HN37 as a potent and chemically stable antiepileptic agent candidate, with an EC50 of 37 nM for KCNQ2[1]. HN37 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
CAS Number
1821222-10-9
UNSPSC
12352005
Target
Potassium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/hn37.html
Concentration
10mM
Purity
99.53
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
FC1=CC=C(CN(CC#C)C2=CC(C)=C(NC(OC)=O)C(C)=C2)C=C1
Molecular Formula
C20H21FN2O2
Molecular Weight
340.39
References & Citations
[1]Yang-Ming Zhang, et al. Discovery of HN37 as a Potent and Chemically Stable Antiepileptic Drug Candidate. J Med Chem. 2021 May 13;64 (9) :5816-5837.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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CatalogName
BA6885-10HN37

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