Nicotinic acid mononucleotide

• UNSPSC Description:

  Nicotinic acid mononucleotide (NAMN) is formed from nicotinic acid (NA) via the nicotinic acid phosphoribosyltransferase in the biosynthesis of NAD+. Nicotinate mononucleotide is a substrate for nicotinamide mononucleotide/Nicotinic acid mononucleotide adenylyltransferase[1][2].

• Target Antigen:

  Others

• Type:

  Natural Products

• Related Pathways:

  Others

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/nicotinic-acid-mononucleotide.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O[C@H]1[C@H]([N+]2=CC=CC(C([O-])=O)=C2)O[C@H](COP(O)(O)=O)[C@H]1O

• Molecular Weight:

  335.20

• References & Citations:

  [1]O'Hara JK, et al. Targeting NAD+ metabolism in the human malaria parasite Plasmodium falciparum. PLoS One. 2014 Apr 18;9(4):e94061.|[2]Khan JA, et al. Nicotinamide adenine dinucleotide metabolism as an attractive target for drug discovery. Expert Opin Ther Targets. 2007 May;11(5):695-705.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  321-02-8