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L-Primapterin

CAT: 0804-HY-119712A-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-119712A-01Size:1 mg
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Description
L-Primapterin (7-Biopterin) is the 7-isomer of L-biopterin. L-Primapterin is a characteristic marker of hyperphenylalaninemia variant primapterinuria, which is excreted in the urine[1][2].
CAS Number
2636-52-4
Product Name Alternative
7-Biopterin
UNSPSC
12352005
Hazard Statement
H315-H319-H335
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/l-primapterin.html
Solubility
10 mM in DMSO
Smiles
O=C1C2=NC=C([C@@H](O)[C@@H](O)C)NC2=NC(N)=N1
Molecular Formula
C9H11N5O3
Molecular Weight
237.22
Precautions
P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362-P403+P233-P405-P501
References & Citations
[1]Curtius HC, et al. Progress in the study of biosynthesis and role of 7-substituted pterins: function of pterin-4a-carbinolamine dehydratase. Adv Exp Med Biol. 1993;338:107-10. |[2]Ayling JE, et al. Hyperphenylalaninemia and 7-pterin excretion associated with mutations in 4a-hydroxy-tetrahydrobiopterin dehydratase/DCoH: analysis of enzyme activity in intestinal biopsies. Mol Genet Metab. 2000 Jul;70 (3) :179-88.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported