L-Leucine-18O2

L-Leucine-18O2

• CAS Number: 73579-45-0
• UNSPSC Description: L-Leucine-18O2 is the 18O-labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway[1].
• Target Antigen: Endogenous Metabolite; Isotope-Labeled Compounds; mTOR
• Type: Isotope-Labeled Compounds
• Related Pathways: Metabolic Enzyme/Protease;Others;PI3K/Akt/mTOR
• Applications: Metabolism-sugar/lipid metabolism
• Field of Research: Metabolic Disease
• Assay Protocol: https://www.medchemexpress.com/l-leucine-18o2.html
• Solubility: 10 mM in DMSO
• Smiles: CC(C)C[C@H](N)C([18OH])=[18O]
• Molecular Weight: 135.17
• References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported