Ferroquine

• Description:

  Ferroquine (Ferrochloroquine), a ferrocenyl analogue of Chloroquine, is an antimalarial agent. Ferroquine shows parasiticidal effect on Plasmodium by inducing oxidative stress and the subsequent destruction of the membrane[1].

• Product Name Alternative:

  Ferrochloroquine; SSR97193

• UNSPSC:

  12352005

• Hazard Statement:

  H315-H319-H335

• Target:

  Parasite

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/Ferroquine.html

• Concentration:

  10mM

• Purity:

  99.68

• Solubility:

  DMSO : 4.35 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles:

  ClC1=CC=C2C(NC[C-]34[Fe+2]56789%10%11([CH-]%12[CH]8=[CH]9[CH]%10=[CH]%11%12)C3(CN(C)C)=[CH]5[CH]6=[CH]47)=CC=NC2=C1

• Molecular Formula:

  C23H24ClFeN3

• Molecular Weight:

  433.75

• Precautions:

  P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501

• References & Citations:

  [1]Keiser J, et al. In vitro and in vivo antischistosomal activity of ferroquine derivatives. Parasit Vectors. 2014 Sep 4;7:424.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  Phase 2

• Isoform:

  Plasmodium

• CAS Number:

  [185055-67-8]