Amoxicillin

• Description:

  Amoxicillin (Amoxycillin) is an antibiotic with good oral absorption and broad spectrum antimicrobial activity. Amoxicillin inhibits the biosynthesis of polypeptides in the cell wall, thereby inhibiting cell growth[1][2][3].

• Product Name Alternative:

  Amoxycillin

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  Antibiotic; Bacterial

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection; Cancer

• Assay Protocol:

  https://www.medchemexpress.com/amoxicillin.html

• Concentration:

  10mM

• Purity:

  98.0

• Solubility:

  DMSO : 83.33 mg/mL (ultrasonic) |H2O : 2 mg/mL (ultrasonic)

• Smiles:

  OC ([C@@H]1N (C2=O) [C@] ([C@@H]2NC ([C@@H] (C3=CC=C (O) C=C3) N) =O) ([H]) SC1 (C) C) =O

• Molecular Formula:

  C16H19N3O5S

• Molecular Weight:

  365.40

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Geddes AM, et al. Introduction: historical perspective and development of amoxicillin/clavulanate. Int J Antimicrob Agents. 2007 Dec;30 Suppl 2:S109-12.|[2]Handsfield HH, et al. Amoxicillin, a new penicillin antibiotic. Antimicrob Agents Chemother. 1973 Feb;3 (2) :262-5.|[3]Guo Y, et, al. Metabolic response of Lactobacillus acidophilus exposed to amoxicillin. J Antibiot (Tokyo) . 2022 May;75 (5) :268-281.|[4]Andes D, et, al. In vivo activities of amoxicillin and amoxicillin-clavulanate against Streptococcus pneumoniae: application to breakpoint determinations. Antimicrob Agents Chemother. 1998 Sep;42 (9) :2375-9.|[5]Kramer MJ, et, al. Activity of oral amoxicillin, ampicillin, and oxytetracycline against infection with chlamydia trachomatis in mice. J Infect Dis. 1979 Jun;139 (6) :717-9.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Scientific Category:

  Reference compound1

• Clinical Information:

  Launched

• Citation 01:

  ACS ES T Water. 2025 Jan 24.|Antimicrob Agents Chemother. 2021 Feb 17;65 (3) :e01921-20.|Arch Microbiol. 2025 Jun 17;207 (8) :177.|Biomed Res Int. 2018 Jul 2:2018:3579832.|bioRxiv. 2024 May 10.|Chemosphere. 2019 Jun:225:378-387.|Chemosphere. 2023 Dec:344:140353.|Environ Sci Pollut Res Int. 2017 Feb;24 (6) :5918-5932.|Genomics. 2022 Nov;114 (6) :110527.|Institute of Chemistry, Federal University of Rio Grande do Sul (UFRGS) . 2017 Nov.|iScience. 2025 Sep 25.|Nat Commun. 2022 Mar 2;13 (1) :1116.|Results Chem. 2024 Oct.|Solvent Extr Lon Exc. 2024 Jul 25.|Talanta. 2025 Jan 1:282:126966.|Vet Microbiol. 2024 May:292:110046.|Drug Metab Pers Ther. 2020 Mar 5;35 (1) :/j/dmdi.2020.35.issue-1/dmpt-2019-0032/dmpt-2019-0032.xml.|Interdisciplinary Graduate School, Nanyang Environment & Water Research Institute. 2020 Mar.|J Fluoresc. 2019 Jan;29 (1) :221-229.|SSRN. 2023 May 30.

• CAS Number:

  26787-78-0