Amoxicillin

• UNSPSC Description:

  Amoxicillin (Amoxycillin) is an antibiotic with good oral absorption and broad spectrum antimicrobial activity. Amoxicillin inhibits the biosynthesis of polypeptides in the cell wall, thereby inhibiting cell growth[1][2][3].

• Target Antigen:

  Antibiotic; Bacterial

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection; Cancer

• Assay Protocol:

  https://www.medchemexpress.com/amoxicillin.html

• Purity:

  98.0

• Solubility:

  DMSO : 83.33 mg/mL (ultrasonic)|H2O : 2 mg/mL (ultrasonic)

• Smiles:

  OC([C@@H]1N(C2=O)[C@]([C@@H]2NC([C@@H](C3=CC=C(O)C=C3)N)=O)([H])SC1(C)C)=O

• Molecular Weight:

  365.40

• References & Citations:

  [1]Geddes AM, et al. Introduction: historical perspective and development of amoxicillin/clavulanate. Int J Antimicrob Agents. 2007 Dec;30 Suppl 2:S109-12.|[2]Handsfield HH,et al. Amoxicillin, a new penicillin antibiotic. Antimicrob Agents Chemother. 1973 Feb;3(2):262-5.|[3]Guo Y, et, al. Metabolic response of Lactobacillus acidophilus exposed to amoxicillin. J Antibiot (Tokyo). 2022 May;75(5):268-281.|[4]Andes D, et, al. In vivo activities of amoxicillin and amoxicillin-clavulanate against Streptococcus pneumoniae: application to breakpoint determinations. Antimicrob Agents Chemother. 1998 Sep;42(9):2375-9.|[5]Kramer MJ, et, al. Activity of oral amoxicillin, ampicillin, and oxytetracycline against infection with chlamydia trachomatis in mice. J Infect Dis. 1979 Jun;139(6):717-9. Antimicrob Agents Chemother. 2021 Feb 17;65(3):e01921-20.|Biomed Res Int. 2018 Jul 2;2018:3579832. |bioRxiv. 2024 May 10.|Chemosphere. 2019 Jun;225:378-387. |Chemosphere. 2023 Oct 3:344:140353.|Environ Sci Pollut Res Int. 2017 Feb;24(6):5918-5932.|Genomics. 2022: 110527.|Institute of Chemistry, Federal University of Rio Grande do Sul (UFRGS). 2017 Nov.|Nat Commun. 2022 Mar 2;13(1):1116.|Results Chem. 2024 Oct.|Solvent Extr Lon Exc. 2024 Jul 25.|Talanta. 2024 Sep 27:282:126966.|Vet Microbiol. 2024 May, 292, 110046.|Drug Metab Pers Ther. 2020 Mar 5;35(1).|Interdisciplinary Graduate School, Nanyang Environment & Water Research Institute. 2020 Mar.|J Fluoresc. 2019 Jan;29(1):221-229. |SSRN. 2023 May 30.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Clinical Information:

  Launched

• CAS Number:

  26787-78-0