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Sorbifolin

CAT: 0804-HY-N11552-04Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N11552-04Size:25 mg
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Description
Sorbifolin, a flavone glucoside, can be isolated from the Pterogyne nitens. Sorbifolin has myeloperoxidase inhibitory and radical scavenging activities. Sorbifolin is also a MPO inhibitor with an IC50 value of 19.2 nM[1].
CAS Number
23130-22-5
UNSPSC
12352005
Target
Glutathione Peroxidase
Type
Natural Products
Related Pathways
Apoptosis; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/sorbifolin.html
Purity
99.62
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1C=C(C2=CC=C(O)C=C2)OC3=CC(OC)=C(C(O)=C13)O
Molecular Formula
C16H12O6
Molecular Weight
300.26
References & Citations
[1]Fernandes DC, et al. Myeloperoxidase inhibitory and radical scavenging activities of flavones from Pterogyne nitens. Chem Pharm Bull (Tokyo) . 2008 May;56 (5) :723-6.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported

Chemical Information

Sorbifolin

Scutellarein 7-methyl ether is a monomethoxyflavone and a trihydroxyflavone. It is functionally related to a scutellarein.

CAS Number23130-22-5
PubChem CID3084390
IUPAC Name5,6-dihydroxy-2-(4-hydroxyphenyl)-7-methoxychromen-4-one
Molecular FormulaC16H12O6
Molecular Weight300.26
XLogP1.7
Topological Polar Surface Area96.2
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count6
Rotatable Bond Count2
Heavy Atom Count22
Formal Charge0
Complexity454
SMILES
COC1=C(C(=C2C(=C1)OC(=CC2=O)C3=CC=C(C=C3)O)O)O
InChI
InChI=1S/C16H12O6/c1-21-13-7-12-14(16(20)15(13)19)10(18)6-11(22-12)8-2-4-9(17)5-3-8/h2-7,17,19-20H,1H3
InChIKey
UWARRXZVZDFPQU-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Sorbifolin
CAS: 23130-22-5
CID: 3084390
Formula: C16H12O6
MW: 300.26
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight300.26
XLogP31.7
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count6
Rotatable Bond Count2
Exact Mass300.06338810
Monoisotopic Mass300.06338810
Topological Polar Surface Area96.2 Ų
Heavy Atom Count22
Formal Charge0
Complexity454
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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