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Lipid C16-C

CAT: 0013-GTR19277681-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19277681-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Lipid C16-C is an ionizable cationic lipid utilized in creating lipid nanoparticles (LNPs) for mRNA delivery both in vitro and in vivo. LNPs with lipid C16-C are preferentially directed to the liver and spleen in mice over other organs such as the lungs, kidneys, lymph nodes, and heart. These LNPs, when encapsulating mRNA for HER2-targeting chimeric antigen receptor (CAR), prompt CAR expression in human macrophages ex vivo and have shown to induce cytotoxic effects in HER2-expressing SKOV3 ovarian cancer cells in vitro.
Storage Conditions
-20°C
Notes
For research use only.

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