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YW2065

CAT: 0013-GTR19277518-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19277518-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
YW2065 has excellent anti-colorectal cancer effects in vitro and in vivo. YW2065 achieves its inhibitory activity for Wnt signaling by stabilizing Axin-1, a scaffolding protein that regulates proteasome degradation of β-catenin. Simultaneously, YW2065 also led to the activation of the tumor suppressor AMPK, providing an additional anticancer mechanism. In addition, YW2065 showed favorable pharmacokinetic properties without obvious toxicity.
CAS Number
2131223-85-1
Smiles
CC=1N (N=CC1C (NC2=NC3=C (C=C2) C=CC=C3) =O) C4=C (Br) C=CC=C4
Molecular Formula
C20H15BrN4O
Molecular Weight
407.26
Storage Conditions
-20°C
Notes
For research use only.

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