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Ceftaroline hydrochloride

CAT: 0013-GTR19277407-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19277407-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ceftaroline hydrochloride (T-91825 HCl, PPI-0903M HCl) is an N-phosphorylated cephalosporin antibiotic and the active form released upon dephosphorylation of the prodrug TAK-599 (ceftaroline fosamil) after it enters the body. Its mechanism of action involves high affinity for penicillin-binding protein 2a (PBP2a), which is associated with methicillin-resistant Staphylococcus aureus (MRSA) resistance (IC50 = 0.90 μg/mL) . Ceftaroline hydrochloride kills various Gram-positive and Gram-negative bacteria by blocking bacterial cell wall synthesis, including resistant strains such as MRSA, methicillin-resistant Staphylococcus epidermidis (MRSE), and Streptococcus pneumoniae.
CAS Number
614758-10-0
Purity
99.25% (May vary between batches)
Smiles
C (O) (=O) C=1N2[C@@] ([C@H] (NC (/C (=N\OCC) /C3=NSC (N) =N3) =O) C2=O) (SCC1SC4=NC (=CS4) C=5C=C[N+] (C) =CC5) [H].[Cl-].Cl
Molecular Formula
C22H22Cl2N8O5S4
Molecular Weight
677.63
Storage Conditions
-20°C
Notes
For research use only.

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