Products for Research Use Only
RegisterLogin

Imarikiren HCl

CAT: 0013-GTR19277370-01Size: 25 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19277370-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Imarikiren is a potent, selective and orally active direct renin inhibitor. TAK-272 shows potent inhibitory activity against human renin (IC50 = 2.1 nM) in hPRA assay and excellent selectivity against other aspartic proteases, such as cathepsin D (IC50 > 10 μM) and pepsin (IC50 > 10 μM) . TAK-272 exhibits a dramatically improved PK profile in rats (F = 25.2%) . TAK-272 (3 and 10 mg/kg, p.o.) exhibits potent and long-lasting antihypertensive efficacy in a dose-dependent manner.
CAS Number
1202269-24-6
Smiles
C (CCCOC) N1C (C (N (CC (C) C) [C@H]2C[C@@H] (C (=O) N3CCOCC3) CNC2) =O) =NC=4C1=CC=CC4.Cl
Molecular Formula
C27H42ClN5O4
Molecular Weight
536.11
Storage Conditions
-20°C
Notes
For research use only.

Related Products

CatalogName
GTR19242156-01Imarikiren
GTR19217874-01Imarikiren hydrochloride
GTR19251246-01AT7519 HCl
GTR19224482-01Octreotide HCl
GTR19224451-01Seproxetine HCl
GTR19223629-01Carbendazim HCl
GTR19223048-01Jervine HCl
GTR19222731-01TPT197 HCl
GTR19219771-01Alpertine HCl
GTR19213500-01Brefonalol HCl

Alternative Products

CatalogName
T202395-01Imarikiren
HY-109034AImarikiren (hydrochloride)
MBS3600731-01Imarikiren hydrochloride
MBS5777304-01Imarikiren HCl

Popular Products