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Phenamil methanesulfonate

CAT: 0013-GTR19277351-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19277351-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Phenamil methanesulfonate is a potent analog of Amiloride that functions as a strong and less reversible epithelial sodium channel (ENaC) blocker with an IC50 of 400 nM, Phenamil methanesulfonate also acts as a competitive inhibitor of TRPP3 and suppressing TRPP3-mediated calcium transport with an IC50 of 140 nM in Ca2+ uptake assays. Phenamil methanesulfonate robustly activates BMP signaling to promote bone repair, supporting its use in cystic fibrosis lung disease, ion channel biology, and regenerative medicine research.
CAS Number
1161-94-0
Purity
98.33% (May vary between batches)
Smiles
O=C (NC (=N) NC=1C=CC=CC1) C2=NC (Cl) =C (N=C2N) N.O=S (=O) (O) C
Molecular Formula
C13H16ClN7O4S
Molecular Weight
401.83
Storage Conditions
-20°C
Notes
For research use only.

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