Products for Research Use Only
RegisterLogin

DIX-01

CAT: 0013-GTR19277089-01Size: 50 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19277089-01Size:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
DIX-01 is a molecular glue degrader that simultaneously induces CRBN-mediated degradation of IKZF1/3 and GSPT1, with DC50 values of 19.80 nM for IKZF1, 45.31 nM for IKZF3, and 120.1 nM for GSPT1. It exhibits potent nanomolar antiproliferative activity across various cancer cell lines. Additionally, DIX-01 induces apoptosis in MV4-11 cells and significantly inhibits the growth of leukemia cells in zebrafish models. This compound is utilized in the study of malignant hematological tumors.
Storage Conditions
-20°C
Notes
For research use only.

Related Products

CatalogName
GTR19218646-01NICE-01
GTR19218479-01DL-01
GTR19215584UCN-01
GTR19201612-01OXA-01
GTR19199398-01CCCI-01
GTR19273791-01WML-01
GTR19350897-01A83-01
GTR19161266-01A77-01
GTR19205641-01HPN-01
GTR19264510-01ACP1-01

Alternative Products

CatalogName
313569DIX domain containing 1
FY-AB44489-01Anti-Dix Domain Containing Protein 1 (DIXDC1)
T3640COS-7-DRA1*01:01/DRB1*01:01 Cell Line
T3637COS-7-DRA1*01:01/DRB5*01:01 Cell Line
MBS2031534-01Recombinant DIX Domain Containing Protein 1 (DIXDC1)
abx616108DIX Domain Containing Protein 1 (DIXDC1) Peptide
T3649COS-7-DRA1*01:01/DRB3*01:01 Cell Line
T3648COS-7-DRA1*01:01/DRB4*01:01 Cell Line
CAU21477-01DIX Domain Containing Protein 1 (DIXDC1) Polyclonal Antibody
RPU41216-01Recombinant Mouse DIX Domain Containing Protein 1 (DIXDC1)

Popular Products