Products for Research Use Only
RegisterLogin

CRBN ligand-448

CAT: 0013-GTR19276312-01Size: 10 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19276312-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
CRBN ligand-448 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), used for recruiting the cereblon protein. It can be linked to a target protein ligand via a linker to form a PROTAC.
CAS Number
2925093-08-7
Smiles
O=CC=1N=CC2=CC=C (C=C2N1) N3C (=O) NC (=O) CC3
Molecular Formula
C13H10N4O3
Molecular Weight
270.25
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

7-(2,4-Dioxo-1,3-diazinan-1-yl)quinazoline-2-carbaldehyde
CAS Number2925093-08-7
PubChem CID169548596
IUPAC Name7-(2,4-dioxo-1,3-diazinan-1-yl)quinazoline-2-carbaldehyde
Molecular FormulaC13H10N4O3
Molecular Weight270.24
XLogP0
Topological Polar Surface Area92.3
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count2
Heavy Atom Count20
Formal Charge0
Complexity428
SMILES
C1CN(C(=O)NC1=O)C2=CC3=NC(=NC=C3C=C2)C=O
InChI
InChI=1S/C13H10N4O3/c18-7-11-14-6-8-1-2-9(5-10(8)15-11)17-4-3-12(19)16-13(17)20/h1-2,5-7H,3-4H2,(H,16,19,20)
InChIKey
XJIAGJOHFOTHSE-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 7-(2,4-Dioxo-1,3-diazinan-1-yl)quinazoline-2-carbaldehyde
CAS: 2925093-08-7
CID: 169548596
Formula: C13H10N4O3
MW: 270.24
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight270.24
XLogP30
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count2
Exact Mass270.07529019
Monoisotopic Mass270.07529019
Topological Polar Surface Area92.3 Ų
Heavy Atom Count20
Formal Charge0
Complexity428
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19249891-01CRBN ligand-16
GTR19249567-01CRBN ligand-148
GTR19249350-01CRBN ligand-14
GTR19249319-01CRBN ligand-164
GTR19249205-01CRBN ligand-45
GTR19249056-01CRBN ligand-183
GTR19240334-01CRBN ligand-11
GTR19277390-01CRBN ligand-337
GTR19277346-01CRBN ligand-413
GTR19277146-01CRBN ligand-297

Alternative Products

CatalogName
HY-W953351CRBN ligand-448
HY-171224CRBN ligand-45
HY-170213CRBN ligand-183
HY-170108CRBN ligand-47
HY-170075CRBN ligand-16
HY-W953523CRBN ligand-693
HY-W953518CRBN ligand-494
HY-W953514CRBN ligand-540
HY-W953511CRBN ligand-493
HY-W953508CRBN ligand-293

Popular Products