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BCFTP

CAT: 0013-GTR19275036-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19275036-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BCFTP is a potent, orally active, and selective positive allosteric modulator of the human Mas-related G protein-coupled receptor X1 (MrgprX1) . It selectively enhances MrgprX1 signaling in HEK293 cells. In a humanized MrgprX1 chronic constriction injury (CCI) mouse model, BCFTP alleviates specific neuropathic pain-related behaviors in an MrgprX1-dependent manner. Additionally, BCFTP synergistically enhances the analgesic effects with psychoactive substances in CCI MrgprX1 mice. This compound can be used for research in neuropathic pain.
CAS Number
2781215-95-8
Smiles
FC1=CC=CC (OC (F) (F) F) =C1OC2=NC=NC=3SC (=C (C=4C=CC (Cl) =CC4) C23) C (C) (C) C
Molecular Formula
C23H17ClF4N2O2S
Molecular Weight
496.9
Storage Conditions
-20°C
Notes
For research use only.

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