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HDAC1-IN-10

CAT: 0013-GTR19274987-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19274987-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
HDAC1-IN-10 (Compound 2b) is a potent, selective, and orally active inhibitor of HDAC1 and HDAC2, with IC50 values of 6 nM and 190 nM, respectively. It exhibits IC50 values greater than 50 μM against HDAC3-8. This compound effectively inhibits the proliferation of HCT-116 cells with a GI50 of 155 nM and suppresses tumor growth in HCT-116 colon cancer xenograft models in nude mice. HDAC1-IN-10 is applicable for colon cancer research.
CAS Number
849233-98-3
Smiles
O=C (OCC=1C=NC=CC1) NCC2=CC=C (C=C2) C (=O) NC=3C=C (C=CC3N) C=4SC=CC4
Molecular Formula
C25H22N4O3S
Molecular Weight
458.54
Storage Conditions
-20°C
Notes
For research use only.

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