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BI1071

CAT: 0013-GTR19274963-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19274963-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BI1071 is an orally active modulator of the Nur77-Bcl-2 apoptotic pathway. It binds to the Nur77-LBD protein with a Kd value of 0.17 μM. BI1071 activates the Nur77 signaling pathway and induces apoptosis by translocating to the mitochondria and interacting with Bcl-2. It inhibits tumor growth in SW620 xenograft mouse models and is applicable in colon cancer research.
Storage Conditions
-20°C
Notes
For research use only.

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