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CZh226 hydrochloride

CAT: 0013-GTR19274898-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19274898-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CZh226 hydrochloride is a potent and selective inhibitor of PAK4, with an IC50 of 18 nM and a selectivity of 346-fold over PAK1. The oral bioavailability of CZh226 hydrochloride is poor, necessitating the use of the prodrug PAK4-IN-1 to enhance absorption and metabolic stability. It is applicable in research on colorectal cancer and melanoma.
CAS Number
2231440-94-9
Smiles
N (C=1C2=C (N=C (C (=O) N3C[C@@H] (C) NCC3) N1) C=CC (Cl) =C2) C=4C=C (NN4) C5CC5.Cl
Molecular Formula
C20H23Cl2N7O
Molecular Weight
448.35
Storage Conditions
-20°C
Notes
For research use only.

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