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ADAMTS-5-IN-4

CAT: 0013-GTR19274831-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19274831-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ADAMTS-5-IN-4 (Compound 4b) is a selective inhibitor of ADAMTS5 with an IC50 of 9.4 μM. It significantly hinders Aggrecan degradation in explant models of osteoarthritis and effectively suppresses pseudopodia extension and directional migration in ovarian cancer cells. ADAMTS-5-IN-4 also exhibits significant cytotoxicity towards HEK293T cells, human chondrocytes, and porcine cartilage explants. This compound is applicable in research related to osteoarthritis and ovarian cancer.
Storage Conditions
-20°C
Notes
For research use only.

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