Products for Research Use Only
RegisterLogin

Razuprotafib sodium

CAT: 0013-GTR19274603-01Size: 50 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19274603-01Size:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Razuprotafib (AKB-9778) sodium is a potent and selective inhibitor of VE-PTP (HPTPη) catalytic activity, with an IC50 of 17 pM. It promotes TIE2 activation, enhances ANG1-induced TIE2 activation, and stimulates phosphorylation of signaling molecules in the TIE2 pathway, including AKT, eNOS, and ERK. Razuprotafib sodium also inhibits the structurally related phosphatase PTP1B with an IC50 of 780 nM. Additionally, apart from HPTPη (IC50 of 36 pM) and HPTPγ (100 pM), it has good selectivity for VE-PTP.
CAS Number
1809275-69-1
Smiles
[C@@H] (CC1=CC=C (NS (=O) (=O) O) C=C1) (NC ([C@H] (CC2=CC=CC=C2) NC (OC) =O) =O) C=3N=C (SC3) C4=CC=CS4.[Na]
Molecular Formula
C26H27N4NaO6S3
Molecular Weight
610.69
Storage Conditions
-20°C
Notes
For research use only.

Related Products

CatalogName
GTR19174231-01Razuprotafib
GTR19157076-01Razuprotafib
GTR19178128-01Emlenoflast sodium (MCC7840 sodium)
GTR19157426-01Cloprostenol sodium
GTR19157418-01Sodium gualenate
GTR19157394-01Sulfachloropyrazine sodium
GTR19156676-01Sulbactum Sodium
GTR19156018-01Sodium stibogluconate
GTR19155572-01Salcaprozate sodium
GTR19155495-01Fluorescein Sodium

Alternative Products

CatalogName
BA8081-10Razuprotafib
AR-R10423-01Razuprotafib-d5
TRC-R128062-50MGRazuprotafib (Phenyl-d5)
1191110 500Sodium Metabisulphite (Sodium Disulphite, Sodium Pyrosulphite)
RM-T081600-01Thiopental Sodium And Sodium Carbonate
21121001-100gSodium caprylate- (Sodium octanoate)
AR-M08542-01Nadroparin Sodium (Heparin Sodium)
31112-64Sodium
030180-01Sodium Metabisulphite (Sodium Disulphite, Sodium Pyrosulphite) 95.0%

Popular Products