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CAB7-3

CAT: 0013-GTR19274593-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19274593-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CAB7-3 is an orally effective HBV capsid assembly modulator that demonstrates excellent antiviral potency. It inhibits HBVDNA with an EC50 of 70 nM and has a CC50 of 32.3 μM. The compound exhibits significant anti-HBV activity across various cell models, with EC50 values of 70 μM in HBV-integrated HepDES19 cells, 1 nM in tetracycline-induced HepAD38 cells, and 2 nM in HBV-infected HLCZ01 cells. In vivo, CAB7-3 effectively reduces hepatic HBV core protein levels and suppresses viral replication. It shows good drug-like properties and safety, making it suitable for hepatitis B virus research.
CAS Number
3014372-17-6
Smiles
C (OCC) (=O) C=1[C@@H] (NC (=NC1CN2[C@@H] (C (NC3=CC=C (B (O) O) C=C3) =O) CCC2) C4=NC=CS4) C5=C (Br) C=C (F) C=C5
Molecular Formula
C28H28BBrFN5O5S
Molecular Weight
656.33
Storage Conditions
-20°C
Notes
For research use only.

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