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LCB-2122

CAT: 0013-GTR19275002-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19275002-01Size:10 mg
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Description
LCB-2122 is an adenosine-like nucleoside analog featuring a C2'-stereoisomeric all-carbon quaternary carbon center. It inhibits doxorubicin-induced myocardial apoptosis with an IC50 value of 0.5 μM and also suppresses imatinib-induced apoptosis. LCB-2122 activates the AMPK signaling pathway, inducing the phosphorylation of AMPK and its downstream substrate acetyl-CoA carboxylase (ACC) . Additionally, LCB-2122 alleviates mitochondrial damage caused by doxorubicin and is used in heart failure research.
CAS Number
2210298-14-7
Smiles
C (O) [C@@]1 (C) [C@@H] (O[C@H] (COP (OCC) (OCC) =O) [C@H]1O) N2C=3C (N=C2) =C (N) N=C (Cl) N3
Molecular Formula
C16H25ClN5O7P
Molecular Weight
465.83
Storage Conditions
-20°C
Notes
For research use only.

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