Products for Research Use Only

MEK-IN-7

CAT: 0013-GTR19275434-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19275434-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MEK-IN-7 (compound WX086) is a potent, orally bioavailable, selective MEK inhibitor with an MEK1 IC50 of 29.62 nM. It effectively inhibits cell proliferation in HT29 and A375 cells, with IC50 values of 0.62 nM and 0.40 nM, respectively, and suppresses tumor growth in HL-29 xenograft mouse models. MEK-IN-7 is applicable in melanoma and colon cancer research.
CAS Number
2256822-22-5
Smiles
O=C1OC2=C (C (=O) N (C (=C2C=3C=CC=C (NS (=O) (=O) C) C3C) C) C4CC4) C (NC5=CC=C (I) C=C5F) =C1C
Molecular Formula
C27H25FIN3O5S
Molecular Weight
649.48
Storage Conditions
-20°C
Notes
For research use only.