Products for Research Use Only

PAR2 modulator-1

CAT: 0013-GTR19274543-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19274543-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PAR2modulator-1 (Compound C781) is an antagonist of the protease-activated receptor 2 (PAR2) . It specifically inhibits the PAR2-dependent MAPK signaling pathway with an IC50 value of 8.5 μM. PAR2modulator-1 can effectively block pain responses triggered by PAR2 agonists. This compound is useful for research in inflammation, immunology, and neurological disorders, including chronic pain and asthma.
CAS Number
2378159-28-3
Smiles
C (=O) (N1C2N ([C@@H] (CC (C) C) C (=O) N (CC3CCNCC3) C2) C (=O) [C@@H] (NC (CC (C) C) =O) C1) C4=CC=CO4
Molecular Formula
C27H41N5O5
Molecular Weight
515.66
Storage Conditions
-20°C
Notes
For research use only.