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USP11-IN-1

CAT: 0013-GTR19274540-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19274540-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
USP11-IN-1 (Compound 26) is a selective inhibitor of ubiquitin-specific protease 11 (USP11) with an IC50 value of 10.9 μM. It displays IC50 values of 18.1 μM for USP4 and greater than 500 μM for USP15, with a selectivity index (SI) of 1.7 and more than 100, respectively. USP11-IN-1 demonstrates significant antiproliferative activity against PEO4 and MDA-MB-231 cells, with IC50 values of 0.47 μM and 6.5 μM, while exhibiting lower cytotoxicity towards MRC-5 cells (IC50 greater than 10 μM) . This compound is applicable in the study of USP11-related malignancies.
Storage Conditions
-20°C
Notes
For research use only.

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