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Selnoflast monopotassium

CAT: 0013-GTR19274528-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19274528-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Selnoflast (RO7486967) monopotassium, also known as Somalix/RG6418/IZD334 monopotassium, is an orally active, potent, selective, and reversible small molecule inhibitor of the NLRP3 inflammasome. It effectively inhibits IL-1β release triggered by NLRP3 activation in monocyte-derived macrophages from human Alzheimer's disease (AD) patients. Selnoflast monopotassium holds promise for research into Alzheimer's disease and systemic inflammatory diseases such as ulcerative colitis and chronic obstructive pulmonary disease.
CAS Number
2260969-37-5
Smiles
[K].O=C (NC=1C2=C (C=C3C1CCC3) CCC2) NS (=O) (=O) C4CCN (CC) CC4
Molecular Formula
C20H30KN3O3S
Molecular Weight
431.64
Storage Conditions
-20°C
Notes
For research use only.

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