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DNDI-0690

CAT: 0013-GTR19274382-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19274382-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DNDI-0690 is a potent and orally active analogue of DNDI-VL-2098, demonstrating significant efficacy against cutaneous leishmaniasis (CL) . It exhibits notable in vitro activity against Leishmania parasites responsible for CL, with an EC50 of 0.17 μM for visceral leishmaniasis and an EC50 of less than 5 μM for the causative parasites of CL. Additionally, DNDI-0690 is effective in a L. major CL mouse model and is applicable for research in CL.
CAS Number
2097881-13-3
Smiles
C (OC=1C=CC (=NC1) C2=CC=C (F) C=C2) [C@@H]3OC=4N (C=C (N (=O) =O) N4) CC3
Molecular Formula
C18H15FN4O4
Molecular Weight
370.34
Storage Conditions
-20°C
Notes
For research use only.

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