Products for Research Use Only
RegisterLogin

ST13

CAT: 0013-GTR19274037-01Size: 50 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19274037-01Size:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
ST13 is an ortho-hydroxyaniline compound that functions as a selective, slow-binding inhibitor of HDAC1 and HDAC2, exhibiting IC50 values of 23 nM and 49 nM, respectively. It shows relatively weaker inhibition for HDAC3 (IC50= 4.30 μM) and HDAC6 (IC50 > 10 μM) . The mechanism of induced binding by ST13 occurs through a two-step process: initially, a rapid formation of the collision complex (EI) between the enzyme and inhibitor occurs, followed by a gradual conversion to a stable complex (E*I) . Additionally, ST13 can induce apoptosis in cancer cells and is applicable in research involving melanoma and triple-negative breast cancer.
CAS Number
1013620-98-8
Smiles
O=C (NC=1C=C (C=CC1O) C=2C=CC=CC2) C3=CC=C (C=C3) NC (=O) C
Molecular Formula
C21H18N2O3
Molecular Weight
346.39
Storage Conditions
-20°C
Notes
For research use only.

Related Products

CatalogName
GTR19273934-01ST17
GTR18138383St18 Antibody
GTR17921710-01ST18 Antibody
GTR17940649ST18 Antibody
GTR17921709-01ST18 Antibody
GTR17928606-01ST14 Antibody
GTR18062568-01ST14 antibody
GTR18152783ST14 Antibody
GTR19055017ST14 Peptide
GTR17888823-01ST14 Antibody

Alternative Products

CatalogName
MBS8536745-01ST13
10R-11141ST13 antibody
GWB-FB2A75ST13, Antibody
DF14493-BPST13 Peptide
OPPA02183-10UGST13 Protein
TS420533P5ST13 CytoSection
ant-536ST13 PAT5C6AT

Popular Products