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UCM1400

CAT: 0013-GTR19273845-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19273845-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
UCM1400 is a melatonin receptor (MT) subtype-selective modulator. It acts as an agonist on MT1 with a pKi value of 7.94 and as an antagonist on MT2 with a pKi value of 8.11. UCM1400 inhibits MT2 receptor-mediated reduction of cyclic adenosine monophosphate (cAMP) with a pIC50 value of 7.87. It exhibits antiproliferative activity on human glioma cells and inhibits tumor growth, making it a potential candidate for cancer research, including studies on gliomas.
Storage Conditions
-20°C
Notes
For research use only.

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